active · antioxidant
Madecassoside
Generally safe·Moderate evidence
A purified triterpene from Centella asiatica (the "cica" plant) used in soothing and barrier-support products, especially Korean formulas. It is well tolerated with a low reported irritation rate; the strong repair and anti-aging claims around it are more marketing than settled evidence.
Questions
- Does madecassoside (cica) actually repair skin, or is it mostly marketing hype?
- Madecassoside is a purified triterpene from the cica plant (Centella asiatica) with clinical evidence of soothing and barrier-support properties, particularly in post-procedure skincare. The evidence for dramatic repair or anti-aging effects is weaker than marketing claims suggest; it is most effective as a calming, barrier-support ingredient for sensitive or compromised skin.
- Is madecassoside safe for all skin types?
- Madecassoside is well tolerated across skin types and is graded low concern in published assessments, with very low reported irritation rates. Recent 2025 clinical studies continue to document favorable safety profiles in skincare formulations.
Products with Madecassoside
- 100Round LabMugwort Calming Serum
- 100MixsoonPeptide Cica Hyalshot
- 100Dr. Althea345 Relief Cream
- 100SKIN1004Madagascar Centella Tone Brightening Capsule Ampoule
- 100AbibHeartleaf TECA Capsule Serum Calming Drop
- 100Dear KlairsFreshly Juiced Vitamin Charging Serum
- 100ONE THINGCentella Asiatica Serum
- 100Etude HouseSoonJung pH 6.5 Whip Cleanser
- 100TorridenBalanceful Cica Serum
- 100Etude HouseSoon Jung 2x Barrier Intensive Cream
- 100Dr.CeuracleCica Regen 92 Toner
- 100NumbuzinNo.1 Clear Filter Sun Essence
- 99MEDIHEALMadecassoside Essential Mask
- 99Round LabMugwort Calming Cream
- 99Dr. Jart+Dermaclear Micro Water
- 99TorridenDIVE IN Serum
- 98Dr. AltheaPure Grinding Cleansing Balm
- 98La Roche-PosayCicaplast Baume B5+
- 98Make P:remUV Defense Me Calming Sun Cream
- 98Pyunkang YulCalming Moisture Serum
- 97AesturaA-Cica 365 Soothing Relief Serum
- 97Some By MiSnail Truecica Miracle Repair Serum
- 97VT CosmeticsReedle Shot 100
- 97VTReedle Shot 100
- 97SupereggSound Renewal Serum Cream
- 96AnuaHeartleaf 77 Clear Pad
- 96Some By MiSnail Truecica Miracle Repair Cream
- 96Real BarrierCicarelief Serum
- 94Dr.JartCicapair Cream
- 94AbibJericho rose PHA toner
- 94Dr.GR.E.D Blemish Soothing Up Moisture Sunscreen
- 94Krave BeautyOil La La 2.0
- 93RaelMicrocrystal Spot Cover
- 93Some By MiAHA BHA PHA 30 Days Miracle Acne Clear Foam
- 93KraveOil La La
- 91GoodalGreen Tangerine Vita C Dark Spot Care Serum
- 90CelimaxDerma Nature Relief Madecica pH Balancing Foam Cleansing
- 90Dear KlairsFreshly Juiced Vitamin Essence Toner
- 89Some By MiTruecica Mineral Calming Tone-Up Suncream
- 88Dr. AltheaSkin Relief Essence
- 88Centellian24Madeca Cream Time Reverse
- 86SKIN1004Madagascar Centella Air-Fit Suncream Plus SPF50+
- 83GoodalGreen Tangerine Vita C Dark Spot Serum
- 83Some By MiRetinol Intense Reactivating Serum
- 83VT CosmeticsCica Skin
- 82InnisfreeVolcanic BHA Pore Cleansing Foam
- 79LaneigeRadian-C Cream
- 79VT CosmeticsAZ Care Cleansing Oil
- 64Some By MiSnail Truecica Miracle Repair Toner
- 60SulwhasooFirst Care Activating Serum VI
References
Cosmetic information for general education, not medical advice. A verdict is a reading of the published evidence, never a guarantee for your skin: any ingredient can irritate someone, so patch test new products and see a professional if you react. Concern is graded on cited evidence, never on hazard-score lists. See how we score.