active · antioxidant
Madecassoside
Generally safe·Moderate evidence
A purified triterpene from Centella asiatica (the "cica" plant) used in soothing and barrier-support products, especially Korean formulas. It is well tolerated with a low reported irritation rate; the strong repair and anti-aging claims around it are more marketing than settled evidence.
Questions
- Does madecassoside (cica) actually repair skin, or is it mostly marketing hype?
- Madecassoside is a purified triterpene from the cica plant (Centella asiatica) with clinical evidence of soothing and barrier-support properties, particularly in post-procedure skincare. The evidence for dramatic repair or anti-aging effects is weaker than marketing claims suggest; it is most effective as a calming, barrier-support ingredient for sensitive or compromised skin.
- Is madecassoside safe for all skin types?
- Madecassoside is well tolerated across skin types and is graded low concern in published assessments, with very low reported irritation rates. Recent 2025 clinical studies continue to document favorable safety profiles in skincare formulations.
Products with Madecassoside
- 100Round LabMugwort Calming Serum
- 100MixsoonPeptide Cica Hyalshot
- 100Dr. Althea345 Relief Cream
- 100SKIN1004Madagascar Centella Tone Brightening Capsule Ampoule
- 98Dr. AltheaPure Grinding Cleansing Balm
- 97AesturaA-Cica 365 Soothing Relief Serum
- 96AnuaHeartleaf 77 Clear Pad
- 94Dr.JartCicapair Cream
- 94AbibJericho rose PHA toner
- 94Dr.GR.E.D Blemish Soothing Up Moisture Sunscreen
- 90CelimaxDerma Nature Relief Madecica pH Balancing Foam Cleansing
- 88Dr. AltheaSkin Relief Essence
- 86SKIN1004Madagascar Centella Air-Fit Suncream Plus SPF50+
- 83GoodalGreen Tangerine Vita C Dark Spot Serum
References
Cosmetic information for general education, not medical advice. A verdict is a reading of the published evidence, never a guarantee for your skin: any ingredient can irritate someone, so patch test new products and see a professional if you react. Concern is graded on cited evidence, never on hazard-score lists. See how we score.