Very High Protection Cream

An organic UV-B filter that also stabilizes other sunscreen actives like avobenzone. The EU SCCS reviewed it and concluded it is safe at current use levels, though rare contact allergy has been reported and older, degraded product may form small amounts of benzophenone.

A solvent and emollient ester used in leave-on and rinse-off formulas. The CIR Expert Panel reviewed alkyl benzoates and found no irritation even at full strength, with typical use levels ranging from 0.0008 to 50 percent depending on product type.

A lightweight humectant and solvent similar in role to propylene glycol, used to carry actives and give lotions a lighter feel. CIR has reviewed it and considers it safe as used in cosmetics.

A silicone that gives a smooth, soft feel and helps hold water in the skin. Inert and well studied.

A broad-spectrum organic UV filter that absorbs both UVB and UVA and also stabilizes other sunscreen filters. The EU SCCS reviewed both the standard and nano particle-size forms and concluded it does not pose a risk to consumers on healthy, intact skin at up to 10 percent, citing negligible skin penetration due to particle size.

A lightweight, volatile silicone that gives serums and primers their silky slip and quick-evaporating finish. Human safety data are reassuring; the EU restriction on this ingredient in rinse-off products is about environmental persistence in waterways, not skin safety.

The base most products are built on. It carries the other ingredients and has no safety concern.

A mineral UV filter and white pigment used in sunscreens and makeup. It sits on the skin surface rather than being absorbed, and major regulators consider it safe for topical cosmetic use.

A widely used organic UV-A filter in sunscreens. It can lose effectiveness in sunlight unless paired with photostabilizers, but safety reviews have not found it to pose a meaningful health hazard at approved use levels.

A broad-spectrum organic UV filter used widely in European and international sunscreens. Approved by the EU and other regulators as safe at cosmetic levels.

A common emulsifier and texture-softener made from glycerin and stearic acid. CIR review of this class found no evidence of reproductive, carcinogenic, sensitizing, or phototoxic effects in the studies examined.

A PEG-based emulsifier that blends oils and water in formulas. It is a workhorse ingredient in stable emulsions and is approved for cosmetic use. Well tolerated.

An emulsifier made from cetyl alcohol and phosphoric acid, used to create stable creams with light conditioning properties. Well tolerated in finished products at cosmetic concentrations.

A lightweight, odorless emollient made by combining coconut or palm-derived fatty acids with glycerin. It spreads easily, feels non-greasy, and has a long history of use in skin and hair products with no meaningful irritation or sensitization signal.

Caprylyl glycol is a plant-derived humectant that also has mild antimicrobial properties, so it is commonly paired with other preservatives to allow lower overall preservative levels. Available data do not point to meaningful irritation or sensitization concerns at typical use levels.

Another sugar-and-fatty-alcohol derived non-ionic surfactant, structurally close to coco-glucoside but made from a shorter (decyl, C10) fatty chain. It is a gentle cleanser generally well tolerated, though a small number of contact-allergy case reports exist, mostly in people with pre-existing skin conditions.

Dimethiconol is a silicone emollient closely related to dimethicone, used to add slip and a smooth finish to creams and serums. It shares dimethicone's long-standing safety record and is considered non-sensitizing and non-comedogenic in typical use.

A chelating agent that binds trace metal ions to keep formulas stable and preservatives working properly. It is not a functional skincare "active" and only a very small amount is used, with minimal skin penetration expected.

A rheology modifier that thickens gels and serums while maintaining a lightweight, non-sticky feel. Provides suspension and stability in water-based formulas. Widely used and well tolerated.

This branched hydrocarbon is one of the isoparaffins the CIR Expert Panel reviewed and found safe as used in cosmetics, including as an emollient in leave-on face creams. It is generally considered non-comedogenic and used mainly to give a lightweight, non-greasy skin feel.

A synthetic surfactant widely used to emulsify oils and water in cosmetics. It is well tolerated and has been used safely in cosmetic formulations for decades.

A small humectant and solvent molecule that helps other ingredients dissolve and helps skin hold water. It is one of the most studied cosmetic ingredients and is considered safe at the concentrations used in personal care products.

A mineral thickener and anti-caking agent widely used in sunscreens and cosmetics to control texture and prevent ingredient separation. CIR has reviewed silica in cosmetic use and found no basis for concern at the levels used topically.

A widely used, gentle preservative also common in food. It is generally well tolerated, though it can occasionally cause mild, transient irritation in people with already-compromised or very reactive skin.

An emulsifier made from sorbitol and isostearic acid, used to stabilize oil-in-water formulas. The Cosmetic Ingredient Review panel assessed it as safe for cosmetic use at typical concentrations.

A fatty alcohol derived from stearic acid that thickens creams and gives them a smooth, non-greasy glide. It is one of the fatty alcohols the CIR panel reviewed together and found safe as used, with a very low reported rate of contact sensitization.

A long-chain alkyl ester derived from behenic acid, used to condition and thicken cosmetic formulations. Available evidence from cosmetic use shows minimal sensitization potential.

Xanthan gum is a microbial-fermentation-derived polysaccharide used to thicken and stabilize textures, similarly common in food. Cosmetic panel review of this and related microbial gums found them safe as used, with no meaningful irritation signal at typical concentrations.