Niacinamide Serum 12% Plus Zinc 2%

The base most products are built on. It carries the other ingredients and has no safety concern.

A form of vitamin B3 used to support a more even-looking tone and a comfortable barrier. Well tolerated at cosmetic levels.

A corn-derived solvent and humectant that has largely replaced propylene glycol in "clean" formulas; CIR reviewed the alkane diol group and found use concentrations up to about 40 percent in leave-on products like deodorant sticks with no meaningful irritation signal.

A humectant that draws water into the skin. One of the best-studied, best-tolerated ingredients in personal care.

Zinc PCA is a zinc salt of a naturally occurring skin humectant, used mainly to help regulate oil and support a balanced skin microbiome in oily or acne-prone formulas. It has a long history of use with no significant reported irritation, though dedicated cosmetic-specific review data is thinner than for more common ingredients.

A humectant that holds water at the skin surface for a more hydrated look. No safety concern.

A silicone that gives a smooth, soft feel and helps hold water in the skin. Inert and well studied.

Caprylyl glycol is a plant-derived humectant that also has mild antimicrobial properties, so it is commonly paired with other preservatives to allow lower overall preservative levels. Available data do not point to meaningful irritation or sensitization concerns at typical use levels.

A widely used preservative, safe at the legal limit of 1% or less. Often the "paraben-free" replacement.

Xanthan gum is a microbial-fermentation-derived polysaccharide used to thicken and stabilize textures, similarly common in food. Cosmetic panel review of this and related microbial gums found them safe as used, with no meaningful irritation signal at typical concentrations.

A widely used, gentle preservative also common in food. It is generally well tolerated, though it can occasionally cause mild, transient irritation in people with already-compromised or very reactive skin.

A more stable, esterified form of vitamin E used as an antioxidant and skin-conditioning ingredient. It is a different substance from the vitamin E acetate implicated in vaping-related lung injury, which involved inhaling the oil, not applying it topically to skin.

This small glycol is used to thin out formulas and help preservatives work better, similar in role to propylene glycol and butylene glycol already in wide use. Industry and EU safety reviewers have set purity and concentration conditions for its use rather than restricting it outright, and no consumer-relevant hazard has been established at typical cosmetic levels.

Used in tiny amounts to set a product to skin-friendly pH. No concern at those levels.