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Neutrogena · Moisturizers

Rapid Wrinkle Repair Retinol Cream

·50 ml·Leave-on
91
Low concern

Why this score

Concern51 / 55
  • Chlorphenesin: watch if sensitive

How much genuine, cited concern the ingredients carry, weighted by how much of each is likely present and whether the product stays on or rinses off.

Transparency20 / 20
  • No hidden fragrance blend.

Whether the full ingredient list, and any fragrance, are actually disclosed.

Formulation restraint20 / 25
  • 3 known irritant or fragrance-allergen ingredients: Chlorphenesin, Retinol, Vitamin C.

Needless irritant or allergen load for the product type. A clean, purposeful formula scores well without any "free-from" theater.

Scored by PlainBody Editorial against the PlainScore method · Label checked July 2026

What’s inside

WaterGenerally safe

The base most products are built on. It carries the other ingredients and has no safety concern.

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Pentaerythrityl TetraethylhexanoateGenerally safe

A multi-ester emollient created from pentaerythritol and ethylhexanoic acid. It provides silky texture and skin conditioning with no documented safety concerns at cosmetic concentrations.

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GlycerinGenerally safe

A humectant that draws water into the skin. One of the best-studied, best-tolerated ingredients in personal care.

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DimethiconeCommonly feared, low concern

A silicone that gives a smooth, soft feel and helps hold water in the skin. Inert and well studied.

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Stearyl AlcoholGenerally safe

A fatty alcohol derived from stearic acid that thickens creams and gives them a smooth, non-greasy glide. It is one of the fatty alcohols the CIR panel reviewed together and found safe as used, with a very low reported rate of contact sensitization.

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Cetearyl AlcoholCommonly feared, low concern

A blend of cetyl and stearyl fatty alcohols used to thicken lotions and soften skin. It is chemically unrelated to drying alcohols like ethanol, and the CIR expert panel has found fatty alcohols safe as used in cosmetics.

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Butylene GlycolCommonly feared, low concern

A lightweight humectant and solvent similar in role to propylene glycol, used to carry actives and give lotions a lighter feel. CIR has reviewed it and considers it safe as used in cosmetics.

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Ceteareth-20Generally safe

A PEG-type emulsifier (ethoxylated cetearyl alcohol) that helps blend the water and oil parts of a cream. CIR concluded ceteareth ingredients are safe as used, with the one caveat that they are not meant for broken or damaged skin.

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IsohexadecaneGenerally safe

This branched hydrocarbon is one of the isoparaffins the CIR Expert Panel reviewed and found safe as used in cosmetics, including as an emollient in leave-on face creams. It is generally considered non-comedogenic and used mainly to give a lightweight, non-greasy skin feel.

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Dimethicone CrosspolymerCommonly feared, low concern

A crosslinked silicone polymer that creates a velvety texture in primers and powders. The crosslinked structure does not change its safety profile, and it is inert and well tolerated.

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CyclopentasiloxaneCommonly feared, low concern

A lightweight, volatile silicone that gives serums and primers their silky slip and quick-evaporating finish. Human safety data are reassuring; the EU restriction on this ingredient in rinse-off products is about environmental persistence in waterways, not skin safety.

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Sodium Acrylates CopolymerGenerally safe

A synthetic gelling and stabilizing polymer that gives lotions and gels their smooth, cushiony texture. The large molecule stays on the skin surface rather than penetrating, and it is graded low concern in published assessments.

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PhenoxyethanolCommonly feared, low concern

A widely used preservative, safe at the legal limit of 1% or less. Often the "paraben-free" replacement.

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Caprylyl GlycolGenerally safe

Caprylyl glycol is a plant-derived humectant that also has mild antimicrobial properties, so it is commonly paired with other preservatives to allow lower overall preservative levels. Available data do not point to meaningful irritation or sensitization concerns at typical use levels.

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ChlorphenesinWatch if sensitive

Chlorphenesin is a preservative subject to an EU maximum concentration limit and has been linked to contact dermatitis in a minority of users, particularly with repeated exposure. Most people tolerate it at the regulated use level without issue.

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Polysorbate 20Generally safe

A widely used emulsifier and solubilizer that has been in cosmetics and pharmaceuticals for decades. The CIR has assessed it as safe with no known concerns at typical cosmetic concentrations. As with any surfactant, some people with very sensitive skin may experience mild irritation.

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RetinolWatch if sensitive

A vitamin A derivative used for the look of lines and texture. Effective but can irritate and increases sun sensitivity; usually advised against in pregnancy.

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BHTCommonly feared, low concern

A small-dose synthetic antioxidant that prevents oils and fragrance in a formula from oxidizing. Not shown to pose a toxicological risk at the levels used in cosmetics.

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Hyaluronic AcidGenerally safe

A humectant that holds water at the skin surface for a more hydrated look. No safety concern.

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Disodium EDTACommonly feared, low concern

A chelating agent that binds trace metal ions to keep formulas stable and preservatives working properly. It is not a functional skincare "active" and only a very small amount is used, with minimal skin penetration expected.

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Sodium HydroxideGenerally safe

A strong alkali used in tiny amounts to adjust the pH of cosmetics to safe, skin-friendly levels. At the pH found in finished products, sodium hydroxide is neutralized and well tolerated.

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Vitamin CWatch if sensitive

The most well-studied form of topical vitamin C, used as an antioxidant and to support collagen signaling and brighten uneven tone. It is acidic and can sting or irritate sensitive skin, and it oxidizes readily once a bottle is opened, which can reduce its effectiveness rather than create a safety issue.

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Lower-concern alternatives

Same category, higher PlainScore.

Cosmetic information for general education, not medical advice. Concern ratings are evidence-graded and cited on each ingredient page. See how we score.