Regenerist Retinol24 Night Serum

The base most products are built on. It carries the other ingredients and has no safety concern.

A silicone that gives a smooth, soft feel and helps hold water in the skin. Inert and well studied.

A humectant that draws water into the skin. One of the best-studied, best-tolerated ingredients in personal care.

A vitamin A derivative used for the look of lines and texture. Effective but can irritate and increases sun sensitivity; usually advised against in pregnancy.

A form of vitamin B3 used to support a more even-looking tone and a comfortable barrier. Well tolerated at cosmetic levels.

A five-amino-acid peptide lipid that stimulates collagen and elastin synthesis. One of the most established peptides in cosmetics with decades of safe use and no reported sensitization issues.

A crosslinked silicone polymer that creates a velvety texture in primers and powders. The crosslinked structure does not change its safety profile, and it is inert and well tolerated.

A mineral UV filter and white pigment used in sunscreens and makeup. It sits on the skin surface rather than being absorbed, and major regulators consider it safe for topical cosmetic use.

A preservative that works by slowly releasing small amounts of formaldehyde to control microbial growth. This makes it an effective preservative, but people with a known formaldehyde or fragrance-type sensitivity may develop irritation or an allergic reaction, especially with prolonged use of leave-on products.

A naturally occurring mineral silicate that adds shimmer and light-diffusing properties to cosmetics. Cosmetic-grade mica is well tolerated and should be free of asbestos and talc contamination.

A widely used emulsifier and solubilizer that has been in cosmetics and pharmaceuticals for decades. The CIR has assessed it as safe with no known concerns at typical cosmetic concentrations. As with any surfactant, some people with very sensitive skin may experience mild irritation.

Dimethiconol is a silicone emollient closely related to dimethicone, used to add slip and a smooth finish to creams and serums. It shares dimethicone's long-standing safety record and is considered non-sensitizing and non-comedogenic in typical use.

A chelating agent that binds trace metal ions to keep formulas stable and preservatives working properly. It is not a functional skincare "active" and only a very small amount is used, with minimal skin penetration expected.