Rejuveness Anti-Wrinkle Cream

The base most products are built on. It carries the other ingredients and has no safety concern.

A larger, gentler alpha hydroxy acid than glycolic acid, used to exfoliate and to draw in moisture. It can still cause stinging or increased sun sensitivity at higher concentrations, so daytime SPF use is sensible, but it is generally better tolerated than glycolic acid.

A humectant that draws water into the skin. One of the best-studied, best-tolerated ingredients in personal care.

A lightweight humectant and solvent similar in role to propylene glycol, used to carry actives and give lotions a lighter feel. CIR has reviewed it and considers it safe as used in cosmetics.

A fatty alcohol used to soften skin and stabilize creams. Despite the name, it does not dry the skin.

A palm/coconut-derived fatty ester used to soften skin and help dissolve oil-soluble UV filters. It sits fairly high on lab comedogenicity scales, so some acne-prone users report clogged pores, though this does not translate into a broader safety concern for general use.

A surfactant derived from stearyl alcohol with a higher degree of ethoxylation than Steareth-2, providing enhanced emulsification. It is graded safe for cosmetic use and well tolerated.

A silicone that gives a smooth, soft feel and helps hold water in the skin. Inert and well studied.

A highly refined, purified oil that forms a light protective layer to slow water loss from skin. Cosmetic-grade mineral oil goes through purification steps that remove the contaminants associated with crude petroleum, and CIR has found it safe as used.

A widely used UVB chemical filter with a long safety record at US-approved concentrations. Some lab and animal studies have raised questions about hormone activity and coral reef impact, which is why a few jurisdictions cap or restrict it, but human-relevant risk at labeled use levels is considered low by regulators.

A gentle surfactant derived from stearyl alcohol and ethylene oxide. It is used to stabilize emulsions and is well tolerated in rinse-off and leave-on formulas. Approved for cosmetic use.

Used like sodium hydroxide to adjust pH in cosmetics at very low levels. At finished-product pH, it is neutralized and well tolerated.

A naturally occurring fatty acid (also made in the body and found in many foods) used to thicken lotions and help stabilize cleansing bars. It is one of the most well-studied emollient ingredients and is not a meaningful irritant at cosmetic use levels.

A widely used preservative, safe at the legal limit of 1% or less. Often the "paraben-free" replacement.

A rheology modifier that thickens gels and serums while maintaining a lightweight, non-sticky feel. Provides suspension and stability in water-based formulas. Widely used and well tolerated.

An undisclosed scent blend that can contain dozens of components. The single most common cause of cosmetic contact allergy, and the blend is not itemized, so you cannot see what is in it.

This branched hydrocarbon is one of the isoparaffins the CIR Expert Panel reviewed and found safe as used in cosmetics, including as an emollient in leave-on face creams. It is generally considered non-comedogenic and used mainly to give a lightweight, non-greasy skin feel.

A preservative that keeps products free of mold and bacteria. Reviewed repeatedly and considered safe at the low levels used.

A cellulose derivative used to thicken and stabilize formulas. It dissolves fully in water and does not separate or settle over time. It is well tolerated and widely used in gels, lotions, and serums.

Dimethiconol is a silicone emollient closely related to dimethicone, used to add slip and a smooth finish to creams and serums. It shares dimethicone's long-standing safety record and is considered non-sensitizing and non-comedogenic in typical use.

Xanthan gum is a microbial-fermentation-derived polysaccharide used to thicken and stabilize textures, similarly common in food. Cosmetic panel review of this and related microbial gums found them safe as used, with no meaningful irritation signal at typical concentrations.

A chelating agent that binds trace metal ions to keep formulas stable and preservatives working properly. It is not a functional skincare "active" and only a very small amount is used, with minimal skin penetration expected.

A more stable, esterified form of vitamin E used as an antioxidant and skin-conditioning ingredient. It is a different substance from the vitamin E acetate implicated in vaping-related lung injury, which involved inhaling the oil, not applying it topically to skin.

A member of the paraben family used to prevent microbial growth in cosmetics. Like methylparaben, it has been reviewed extensively and found safe at the concentrations used in leave-on and rinse-off products.

An organic UV filter with a genuinely mixed evidence picture: it is a documented contact and photo-contact allergen in a subset of users, and studies show it absorbs into the bloodstream at levels that prompted the FDA to request further safety data. The EU has lowered its permitted concentration as a precaution. It is not established as unsafe at approved levels, but people with sensitive skin may prefer to watch for reactions or choose a mineral filter.

A synthetic surfactant widely used to emulsify oils and water in cosmetics. It is well tolerated and has been used safely in cosmetic formulations for decades.

An antioxidant that helps protect a formula and condition skin. Well tolerated.

A small-dose synthetic antioxidant that prevents oils and fragrance in a formula from oxidizing. Not shown to pose a toxicological risk at the levels used in cosmetics.

A waxy sterol found naturally in skin and used in cosmetics as an emollient and emulsifier. It supports the skin barrier and is well tolerated across skin types.

A rose-scented fragrance ingredient found naturally in geranium and rose oil. It is one of the 26 fragrance allergens the EU requires to be labeled by name because a minority of people develop skin sensitization to it, though most users tolerate it without issue.

A sweet, hay-like fragrance ingredient naturally found in tonka bean and lavender. It is one of the 26 EU-designated fragrance allergens and is also subject to an EU maximum concentration limit in finished cosmetic products.

A floral, rose-like fragrance compound found in many essential oils. It is one of the 26 EU-designated fragrance allergens, meaning a documented minority of people can develop contact sensitization, so brands must disclose it above set thresholds.

A jasmine-like fragrance compound frequently used in soaps and lotions. It is one of the 26 EU-designated fragrance allergens, though studies suggest its sensitization potency is comparatively low relative to other listed allergens.

A citrus-scented fragrance component. Fine for most, but it oxidizes over time into a known contact allergen, so it must be labelled in the EU.

A floral fragrance component and one of the EU-labelled fragrance allergens. Usually fine, worth watching if you react to scented products.

A mineral UV filter and white pigment used in sunscreens and makeup. It sits on the skin surface rather than being absorbed, and major regulators consider it safe for topical cosmetic use.