Advanced Therapy Lotion

The base most products are built on. It carries the other ingredients and has no safety concern.

A humectant that draws water into the skin. One of the best-studied, best-tolerated ingredients in personal care.

A naturally occurring fatty acid (also made in the body and found in many foods) used to thicken lotions and help stabilize cleansing bars. It is one of the most well-studied emollient ingredients and is not a meaningful irritant at cosmetic use levels.

A wax-like ester of ethylene glycol and stearic acid used purely to thicken shampoo/conditioner and give it a pearly opaque look; it has no cleansing or active role. CIR found it non-sensitizing and non-irritating even at high test concentrations, and decades of manufacturer exposure data show no reported health effects.

A fatty alcohol used to soften skin and stabilize creams. Despite the name, it does not dry the skin.

A silicone that gives a smooth, soft feel and helps hold water in the skin. Inert and well studied.

A time-tested occlusive that seals in moisture and helps damaged skin heal, widely used in dermatology for wound care. Cosmetic-grade petrolatum must meet purity standards that remove the polycyclic aromatic hydrocarbons found in crude sources, and it is considered one of the most effective and well-studied barrier ingredients available.

A mineral clay-like absorbent used in powder formulations and dry textures to control oil and provide body. It is widely used in cosmetics, though inhalation of powder particles should be minimized during application.

An undisclosed scent blend that can contain dozens of components. The single most common cause of cosmetic contact allergy, and the blend is not itemized, so you cannot see what is in it.

A preservative that works by slowly releasing small amounts of formaldehyde to control microbial growth. This makes it an effective preservative, but people with a known formaldehyde or fragrance-type sensitivity may develop irritation or an allergic reaction, especially with prolonged use of leave-on products.

Carbomer is a synthetic polymer used purely to thicken and stabilize gels and lotions, with negligible skin penetration due to its large molecular size. Safety reviews have found low toxicity and minimal irritation potential even in leave-on use.

A chelating agent that binds trace metal ions to keep formulas stable and preservatives working properly. It is not a functional skincare "active" and only a very small amount is used, with minimal skin penetration expected.

A buffering agent used in small amounts to maintain or adjust the pH of formulas to keep them skin-friendly. It is not added as an active ingredient but to keep the product at a safe and stable pH level.

A more stable, esterified form of vitamin E used as an antioxidant and skin-conditioning ingredient. It is a different substance from the vitamin E acetate implicated in vaping-related lung injury, which involved inhaling the oil, not applying it topically to skin.

Retinyl palmitate is an ester of vitamin A used in moisturizers and some sunscreens for mild anti-aging and antioxidant support. Long-term panel reviews of the ingredient have generally found it safe as used, with irritation potential similar to other mild retinoids at typical cosmetic concentrations.

A linoleic-acid-rich plant oil used as an emollient and, in some small pediatric studies, associated with support of the skin barrier when applied to infant skin. It is well tolerated with a low reported rate of contact reactions.

A mineral UV filter and white pigment used in sunscreens and makeup. It sits on the skin surface rather than being absorbed, and major regulators consider it safe for topical cosmetic use.