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The Ordinary · Serums

Argireline Solution 10%

$9.7·30 ml·Leave-on
93
Low concern

Why this score

Concern51 / 55
  • Chlorphenesin: watch if sensitive

How much genuine, cited concern the ingredients carry, weighted by how much of each is likely present and whether the product stays on or rinses off.

Transparency20 / 20
  • No hidden fragrance blend.

Whether the full ingredient list, and any fragrance, are actually disclosed.

Formulation restraint22 / 25
  • 1 known irritant or fragrance-allergen ingredient: Chlorphenesin.

Needless irritant or allergen load for the product type. A clean, purposeful formula scores well without any "free-from" theater.

Scored by PlainBody Editorial against the PlainScore method · Label checked July 2026

What’s inside

WaterGenerally safe

The base most products are built on. It carries the other ingredients and has no safety concern.

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PropanediolGenerally safe

A corn-derived solvent and humectant that has largely replaced propylene glycol in "clean" formulas; CIR reviewed the alkane diol group and found use concentrations up to about 40 percent in leave-on products like deodorant sticks with no meaningful irritation signal.

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Acetyl Hexapeptide-8Generally safe

A hexapeptide designed to reduce facial muscle contractions by interfering with acetylcholine release. Cosmetic-grade formulations show no systemic absorption at recommended use levels and are well tolerated.

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Sodium ChlorideCommonly feared, low concern

Ordinary salt, used in surfactant-based products like shampoos and body washes to adjust viscosity by interacting with the surfactant micelles. It has no meaningful toxicity concern at cosmetic use levels; the main practical downside is that too much can make a formula feel less mild.

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Potassium SorbateGenerally safe

A widely used, gentle preservative also common in food. It is generally well tolerated, though it can occasionally cause mild, transient irritation in people with already-compromised or very reactive skin.

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PhenoxyethanolCommonly feared, low concern

A widely used preservative, safe at the legal limit of 1% or less. Often the "paraben-free" replacement.

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ChlorphenesinWatch if sensitive

Chlorphenesin is a preservative subject to an EU maximum concentration limit and has been linked to contact dermatitis in a minority of users, particularly with repeated exposure. Most people tolerate it at the regulated use level without issue.

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Lower-concern alternatives

Same category, higher PlainScore.

Cosmetic information for general education, not medical advice. Concern ratings are evidence-graded and cited on each ingredient page. See how we score.