Supreme Screen SPF 50+

The base most products are built on. It carries the other ingredients and has no safety concern.

A lightweight, volatile silicone that gives serums and primers their silky slip and quick-evaporating finish. Human safety data are reassuring; the EU restriction on this ingredient in rinse-off products is about environmental persistence in waterways, not skin safety.

A humectant that draws water into the skin. One of the best-studied, best-tolerated ingredients in personal care.

A lightweight humectant and solvent similar in role to propylene glycol, used to carry actives and give lotions a lighter feel. CIR has reviewed it and considers it safe as used in cosmetics.

A silicone that gives a smooth, soft feel and helps hold water in the skin. Inert and well studied.

A blend of cetyl and stearyl fatty alcohols used to thicken lotions and soften skin. It is chemically unrelated to drying alcohols like ethanol, and the CIR expert panel has found fatty alcohols safe as used in cosmetics.

A rheology modifier that thickens gels and serums while maintaining a lightweight, non-sticky feel. Provides suspension and stability in water-based formulas. Widely used and well tolerated.

A PEG-type emulsifier (ethoxylated cetearyl alcohol) that helps blend the water and oil parts of a cream. CIR concluded ceteareth ingredients are safe as used, with the one caveat that they are not meant for broken or damaged skin.

A stable, saturated version of squalene, a lipid the skin already produces, now usually sourced from olives or sugarcane instead of shark liver. It is very well tolerated across skin types and helps reinforce the skin barrier.

Caprylyl glycol is a plant-derived humectant that also has mild antimicrobial properties, so it is commonly paired with other preservatives to allow lower overall preservative levels. Available data do not point to meaningful irritation or sensitization concerns at typical use levels.

A PEG-based emulsifier that blends oils and water in formulas. It is a workhorse ingredient in stable emulsions and is approved for cosmetic use. Well tolerated.

A mineral thickener and anti-caking agent widely used in sunscreens and cosmetics to control texture and prevent ingredient separation. CIR has reviewed silica in cosmetic use and found no basis for concern at the levels used topically.

A naturally derived humectant made from fermented plant sugars that draws water into the skin. It is well tolerated in cosmetics and is used to support hydration and skin softness.

Another sugar-and-fatty-alcohol derived non-ionic surfactant, structurally close to coco-glucoside but made from a shorter (decyl, C10) fatty chain. It is a gentle cleanser generally well tolerated, though a small number of contact-allergy case reports exist, mostly in people with pre-existing skin conditions.

A more stable, esterified form of vitamin E used as an antioxidant and skin-conditioning ingredient. It is a different substance from the vitamin E acetate implicated in vaping-related lung injury, which involved inhaling the oil, not applying it topically to skin.

A chelating agent that binds trace metal ions to keep formulas stable and preservatives working properly. It is not a functional skincare "active" and only a very small amount is used, with minimal skin penetration expected.

A synthetic surfactant widely used to emulsify oils and water in cosmetics. It is well tolerated and has been used safely in cosmetic formulations for decades.

Pentylene glycol is a humectant and solvent that also offers mild antimicrobial support in formulas. It is generally well tolerated, with only rare reports of irritation, mostly in already sensitive or compromised skin.

A small humectant and solvent molecule that helps other ingredients dissolve and helps skin hold water. It is one of the most studied cosmetic ingredients and is considered safe at the concentrations used in personal care products.

Xanthan gum is a microbial-fermentation-derived polysaccharide used to thicken and stabilize textures, similarly common in food. Cosmetic panel review of this and related microbial gums found them safe as used, with no meaningful irritation signal at typical concentrations.

Used in tiny amounts to set a product to skin-friendly pH. No concern at those levels.

Ordinary salt, used in surfactant-based products like shampoos and body washes to adjust viscosity by interacting with the surfactant micelles. It has no meaningful toxicity concern at cosmetic use levels; the main practical downside is that too much can make a formula feel less mild.