Gluconolactone

Gluconolactone is a polyhydroxy acid that exfoliates gently while also acting as a humectant and mild antioxidant, and it is generally recommended for sensitive or barrier-compromised skin over smaller AHAs. A full cosmetic panel review found it safe as used, though some users still report mild stinging or redness at higher concentrations.

Cosmetic information for general education, not medical advice. A verdict is a reading of the published evidence, never a guarantee for your skin: any ingredient can irritate someone, so patch test new products and see a professional if you react. Concern is graded on cited evidence, never on hazard-score lists. See how we score.