Mandelic Acid Serum

The base most products are built on. It carries the other ingredients and has no safety concern.

Mandelic acid is a larger-molecule alpha hydroxy acid that tends to penetrate skin more slowly than glycolic acid, which is generally associated with less stinging and redness. It carries the same general AHA cautions around sun sensitivity but is often better tolerated by reactive skin.

A corn-derived solvent and humectant that has largely replaced propylene glycol in "clean" formulas; CIR reviewed the alkane diol group and found use concentrations up to about 40 percent in leave-on products like deodorant sticks with no meaningful irritation signal.

Used like sodium hydroxide to adjust pH in cosmetics at very low levels. At finished-product pH, it is neutralized and well tolerated.

Gluconolactone is a polyhydroxy acid that exfoliates gently while also acting as a humectant and mild antioxidant, and it is generally recommended for sensitive or barrier-compromised skin over smaller AHAs. A full cosmetic panel review found it safe as used, though some users still report mild stinging or redness at higher concentrations.

A humectant that holds water at the skin surface for a more hydrated look. No safety concern.

A soothing, skin-conditioning compound (also found in comfrey root) commonly added to calm and hydrate irritated or sensitive skin. It has a long history of safe use with very low irritation potential.

A polysaccharide produced by fermentation of fungal cultures, used to thicken and stabilize formulas. It is well tolerated in cosmetics and often chosen by natural-leaning brands. It functions similarly to other gelling agents but comes from a more controlled fermentation source.

A fermentation-derived polysaccharide used to thicken and hydrate formulas. It absorbs and holds water in the skin, contributing to a smooth texture. Limited clinical data but no known sensitizers or safety concerns at cosmetic use levels.

Xanthan gum is a microbial-fermentation-derived polysaccharide used to thicken and stabilize textures, similarly common in food. Cosmetic panel review of this and related microbial gums found them safe as used, with no meaningful irritation signal at typical concentrations.