Day Cream

The base most products are built on. It carries the other ingredients and has no safety concern.

A fatty acid ester derived from isostearic acid and isopropyl alcohol, valued for its lightweight emollient properties and smooth feel on skin. It is an inert conditioning agent with minimal risk of irritation at typical cosmetic use levels.

A humectant that draws water into the skin. One of the best-studied, best-tolerated ingredients in personal care.

A lightweight humectant and solvent similar in role to propylene glycol, used to carry actives and give lotions a lighter feel. CIR has reviewed it and considers it safe as used in cosmetics.

A lightweight, volatile silicone that gives serums and primers their silky slip and quick-evaporating finish. Human safety data are reassuring; the EU restriction on this ingredient in rinse-off products is about environmental persistence in waterways, not skin safety.

A stable, saturated version of squalene, a lipid the skin already produces, now usually sourced from olives or sugarcane instead of shark liver. It is very well tolerated across skin types and helps reinforce the skin barrier.

A rich plant butter pressed from shea tree nuts, valued for softening and cushioning dry skin. It is generally well tolerated, though very rare allergic reactions have been reported and people with tree nut allergies who are cautious may want to patch test first.

A smooth synthetic emollient ester used to soften skin and carry oil-soluble ingredients. It is well tolerated and graded low concern in published assessments.

A soothing humectant that helps skin and hair look conditioned. Very well tolerated.

A more stable, esterified form of vitamin E used as an antioxidant and skin-conditioning ingredient. It is a different substance from the vitamin E acetate implicated in vaping-related lung injury, which involved inhaling the oil, not applying it topically to skin.

A widely used preservative, safe at the legal limit of 1% or less. Often the "paraben-free" replacement.

A fatty alcohol used to soften skin and stabilize creams. Despite the name, it does not dry the skin.

Derived from olive oil fatty acids, this PEG-free emulsifier is used at low concentrations to hold water and oil phases together in creams. Available safety and dermatological testing has not shown meaningful irritation or sensitization at use levels.

A silicone that gives a smooth, soft feel and helps hold water in the skin. Inert and well studied.

An emulsifier made from cetyl alcohol and phosphoric acid, used to create stable creams with light conditioning properties. Well tolerated in finished products at cosmetic concentrations.

A small humectant and solvent molecule that helps other ingredients dissolve and helps skin hold water. It is one of the most studied cosmetic ingredients and is considered safe at the concentrations used in personal care products.

An olive-oil-derived emulsifier, almost always paired with cetearyl olivate, that holds water and oil together and leaves a light skin-like finish. It is well tolerated and graded low concern in published assessments.

A humectant sugar alcohol that draws water into the skin. It is well tolerated and widely used in skincare and food. Not known to cause concern at the concentrations used in cosmetics.

A synthetic gelling and stabilizing polymer that gives lotions and gels their smooth, cushiony texture. The large molecule stays on the skin surface rather than penetrating, and it is graded low concern in published assessments.

A high molecular weight polymer used to thicken and gel aqueous formulas in creams and lotions. Its large size prevents skin penetration, and CIR has confirmed it is safe as used in cosmetics.

A glycerin derivative used as a skin conditioner and preservative booster, often paired with phenoxyethanol to allow lower total preservative levels. It has a low irritation and sensitization profile in safety reviews.

A crosslinked acrylic polymer that thickens and stabilizes formulations. Published assessments show it to be well tolerated at cosmetic use levels, with no evidence of penetration into viable skin layers or systemic absorption.

A basic amino acid naturally found in skin that draws moisture into the stratum corneum. It is well tolerated in cosmetics at typical concentrations and has been used safely in skincare formulations for decades.

A synthetic film-forming emollient that provides a protective, flexible layer on skin. Not absorbed and well tolerated with no documented safety issues in cosmetic use.

A chelating agent that binds trace metal ions to keep formulas stable and preservatives working properly. It is not a functional skincare "active" and only a very small amount is used, with minimal skin penetration expected.

Xanthan gum is a microbial-fermentation-derived polysaccharide used to thicken and stabilize textures, similarly common in food. Cosmetic panel review of this and related microbial gums found them safe as used, with no meaningful irritation signal at typical concentrations.

A humectant that holds water at the skin surface for a more hydrated look. No safety concern.

A widely used emulsifier and solubilizer that has been in cosmetics and pharmaceuticals for decades. The CIR has assessed it as safe with no known concerns at typical cosmetic concentrations. As with any surfactant, some people with very sensitive skin may experience mild irritation.

A naturally occurring lactone form of panthenol (provitamin B5) that functions as a skin conditioning and hydrating agent. It is chemically related to panthenol with a comparable safety profile established through cosmetic use.

Carbomer is a synthetic polymer used purely to thicken and stabilize gels and lotions, with negligible skin penetration due to its large molecular size. Safety reviews have found low toxicity and minimal irritation potential even in leave-on use.

A mild non-ionic cleansing agent made from coconut fatty alcohols and plant sugars (glucose). It is widely used in sulfate-free shampoos and gentle cleansers and is one of the least irritating surfactants in common use.

A signal peptide attached to palmitic acid that activates collagen synthesis in skin cells. Well tolerated across skin types with no significant safety concerns in cosmetic use.

A peptide lipid that mimics collagen fragments and signals skin cells to increase collagen production while reducing inflammation. Established in anti-aging formulas with a consistent safety record.