Madagascar Centella Hyalu-Cica Blue Serum

The base most products are built on. It carries the other ingredients and has no safety concern.

A plant extract long used in traditional wound care and now common in "cica" soothing products, valued for calming redness and supporting the skin barrier. It is generally well tolerated, with rare contact allergy reported.

A lightweight humectant and solvent similar in role to propylene glycol, used to carry actives and give lotions a lighter feel. CIR has reviewed it and considers it safe as used in cosmetics.

A form of vitamin B3 used to support a more even-looking tone and a comfortable barrier. Well tolerated at cosmetic levels.

A humectant that draws water into the skin. One of the best-studied, best-tolerated ingredients in personal care.

A humectant that holds water at the skin surface for a more hydrated look. No safety concern.

A broken-down form of hyaluronic acid with smaller molecules intended to penetrate more deeply into the skin. It functions as a humectant and is well tolerated, with the same safety profile as standard hyaluronic acid.

A small glycol used as a solvent and to boost the absorption of actives, and to help preservatives work at lower levels. It is well tolerated and graded low concern in published assessments.

A soothing humectant that helps skin and hair look conditioned. Very well tolerated.

Derived from olive oil fatty acids, this PEG-free emulsifier is used at low concentrations to hold water and oil phases together in creams. Available safety and dermatological testing has not shown meaningful irritation or sensitization at use levels.

Carbomer is a synthetic polymer used purely to thicken and stabilize gels and lotions, with negligible skin penetration due to its large molecular size. Safety reviews have found low toxicity and minimal irritation potential even in leave-on use.

A basic amino acid naturally found in skin that draws moisture into the stratum corneum. It is well tolerated in cosmetics at typical concentrations and has been used safely in skincare formulations for decades.

An olive-oil-derived emulsifier, almost always paired with cetearyl olivate, that holds water and oil together and leaves a light skin-like finish. It is well tolerated and graded low concern in published assessments.

A lightweight, odorless emollient made by combining coconut or palm-derived fatty acids with glycerin. It spreads easily, feels non-greasy, and has a long history of use in skin and hair products with no meaningful irritation or sensitization signal.

Pentylene glycol is a humectant and solvent that also offers mild antimicrobial support in formulas. It is generally well tolerated, with only rare reports of irritation, mostly in already sensitive or compromised skin.

A naturally occurring nucleoside used in anti-aging formulas, often marketed for smoothing the look of fine lines. It has a low irritation profile and no established hazard at cosmetic use levels.

An amino acid polymer derived from glutamic acid that functions as a humectant to draw moisture into skin. It is graded with no known concerns in cosmetic use and is well tolerated across skin types.

A hydrosol from damascena rose flowers, used as a skin toner and fragrance. Rose can trigger allergic contact dermatitis in sensitive individuals, though the hydrosol form is generally well tolerated. People with a history of plant sensitivities should patch test.

A glycerin derivative used as a skin conditioner and preservative booster, often paired with phenoxyethanol to allow lower total preservative levels. It has a low irritation and sensitization profile in safety reviews.

Sodium phytate is a plant-derived chelating agent used to bind trace metals and stabilize formulas, often as a preservative booster alongside other preservatives. Available safety reviews have not identified meaningful irritation or sensitization concerns at typical use levels.

Xanthan gum is a microbial-fermentation-derived polysaccharide used to thicken and stabilize textures, similarly common in food. Cosmetic panel review of this and related microbial gums found them safe as used, with no meaningful irritation signal at typical concentrations.

A starch derivative used in cosmetics to thicken formulations and improve texture. It has been used safely in food and cosmetics for decades and shows low irritation potential across rinse-off and leave-on products.

A naturally occurring lactone form of panthenol (provitamin B5) that functions as a skin conditioning and hydrating agent. It is chemically related to panthenol with a comparable safety profile established through cosmetic use.

A phospholipid emulsifier from soy or sunflower that binds water and oil and helps other ingredients absorb. It is a natural component of skin membranes, well tolerated, and reviewed as safe as used; a soy-derived grade is not a meaningful concern for a soy food allergy because the protein is largely absent.

A lab-made version of a lipid naturally found in the outer skin barrier. It is added to creams and cleansers to help replace lipids that washing can strip away, and it is not linked to irritation or safety concerns.

A chemically cross-linked form of sodium hyaluronate designed to remain on the skin surface longer and provide sustained hydration. It functions as a humectant and is well tolerated, with the same safety profile as standard hyaluronic acid.

A lower molecular weight version of hyaluronic acid designed for better skin penetration. It has been extensively studied and shown to support skin hydration and barrier function with excellent tolerability in diverse formulations and skin types.