emollient · antioxidant
Phytosphingosine
Generally safe·Moderate evidence
A plant-derived lipid precursor found naturally in skin that supports barrier function and lipid composition. It is used in skincare formulations to strengthen the stratum corneum and is documented as well tolerated, though rare individual sensitivities may occur.
Questions
- Is phytosphingosine safe for sensitive skin?
- Phytosphingosine is a ceramide precursor found in skin barrier lipids. Published safety data is limited but supportive, and it's used in products marketed for sensitive or compromised skin. Individual reactions vary.
- What does phytosphingosine do?
- It's a building block for ceramides, the fats that help seal the skin barrier. Products use it to support barrier repair, though direct clinical evidence for topical benefit is modest.
Products with Phytosphingosine
- 100CliniqueAll About Eyes Eye Cream with Vitamin C
- 100Tower28SOS FaceGuard SPF 30
- 100The Jojoba CompanyHydrating Peptide Day Cream
- 100up&upDaily Moisturizing Lotion
- 100Up & UpMoisturizer with Salicylic Acid Acne Treatment
- 100WalgreensAdvanced Moisturizing Cream
- 100CeraVeFoaming Face Wash
- 99IlliyoonCeramide Ato Gentle Skin Toner
- 99EquateBeauty Hydrating Cleanser
- 98CeraVeHydrating Facial Toner
- 98Up & UpSalicylic Acid Acne Wash
- 97Paula's ChoiceOmega+ Complex Moisturizer
- 97CliniqueAll About Eyes Rich Eye Cream with Hyaluronic Acid
- 97CeraVeEczema Relief Moisturizing Cream
- 97SkinfixEczema+ Pre-Biotic Foaming Oil Cleanser
- 97IsntreeHyper Retinol EX 1.0 Serum
- 97CeraVeUltra-Light Moisturizing Lotion SPF 30
- 96Up & UpBenzoyl Peroxide Acne Wash
- 96EquateBeauty Moisturizing Lotion
- 95AnuaRice 70 Glow Milky Toner
- 94Hero CosmeticsGentle Milky Cleanser
- 94CurelItch Defense Lotion
- 94EquateBeauty Foaming Facial Cleanser
- 93CeraVeFacial Moisturizing Lotion AM Lightweight SPF 50
- 93CliniqueAll About Eyes Rich
- 91CeraVeAcne Control Gel
- 89Kate SomervilleDeliKate Recovery Serum
- 89DermaticaClarifying Azelaic Acid 20% Cream
- 89CVS HealthAM Moisturizing Facial Broad Spectrum SPF 30 Sunscreen
- 88Centellian24Madeca Cream Time Reverse
- 87Centellian24Expert Madeca Cream Active Renew PDRN
- 85Drunk ElephantProtini Powerpeptide Resurfacing Serum
- 85CeraVeAM Facial Moisturizing Lotion SPF 50
- 84TrulyHydra-Restore Body Lotion
- 84Dr Dennis GrossDermInfusions Fill + Repair Serum with Hyaluronic Acid
- 81Heliocare360 Gel Oil-Free
- 81WalgreensAll-Purpose Psoriasis Wash
- 80e.l.f.Holy Hydration Sleeping Mask
- 79UriageDS Hair Soft Balancing Shampoo
- 61Y.O.U.6% Acid Renewal Peeling Serum
- 53SesdermaAcglicolic Facial Serum
References
Cosmetic information for general education, not medical advice. A verdict is a reading of the published evidence, never a guarantee for your skin: any ingredient can irritate someone, so patch test new products and see a professional if you react. Concern is graded on cited evidence, never on hazard-score lists. See how we score.